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Evolution in Health and Medicine Sackler Colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

Mamuka Khvedelidze–Jan 31, 2010

Neo-Darwinian evolutionary theory is based on exquisite selection of phenotypes caused by small genetic variations, which is the basis of quantitative trait contribution to phenotype and disease. Here, we propose a new non-Lamarckian theory for a role of epigenetics in evolution.

Tags: Evolutionary biology, Genetics, evolution, epigenetics, genetics

Evolution in Health and Medicine Sackler Colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

Authors: Andrew P Feinberg, Rafael A Irizarry

Proceedings of the National Academy of Sciences of the United States of America. 01/2010; (published)

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